lavendustin C ( Lavendustin C | HDBA, NSC 666251 )

产品货号. M17229 CAS No. 125697-93-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

lavendustin C
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Lavendustin C 是表皮生长因子 (EGF) 受体相关酪氨酸激酶的有效抑制剂。
产品描述

Lavendustin C, also known as HDBA and NSC 666251, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 μM.. HDBA inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.
体外实验

Lavendustin C (Compound 5) shows potent inhibitory activity, and it may be the core structure responsible for inhibition of tyrosine kinase. Lavendustin C (10-150 μM) inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.
体内实验

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同义词

Lavendustin C | HDBA, NSC 666251
通路

MAPK/ERK Signaling
靶点

Raf
受体

tyrosine kinase
研究领域

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适应症

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1.Nynca A, et al. Domest Anim Endocrinol. 2013 Jan;44(1):10-8

计算器

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